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Wednesday, November 20, 2013

Why has Foot odor?

foot odor is mainly caused by a cutaneous infection with Micrococcus sedentarius (now renamed to Kytococcus sedentarius); Dermatophilus congolensis; or species of Corynebacterium,Actinomyces, or Streptomyces. Under optimum conditions (ie, prolonged occlusion, hyperhidrosis, increased skin surface pH), these bacteria grow and produce proteinases that destroy the stratum corneum, creating pits. D congolensis liberates keratinases in appropriate substrate. K sedentarius has been found to produce 2 keratin-degrading enzymes. They are protease P1 (30 kd) and P2 (50 kd). The foot odor associated with Foot odor is conume to be the production of sulfur-compound by-products, such as thiols, sulfides, and thioesters.

In 2006, foot odor without pitted skin changes was discovered to be from overgrowth of Bacillus subtilis and specifically an isovaleric acid produced by Staphylococcus epidermidis overgrowth, a normal skin flora.


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