foot odor
is mainly caused by a cutaneous infection with Micrococcus
sedentarius (now renamed to Kytococcus sedentarius); Dermatophilus
congolensis; or species of Corynebacterium,Actinomyces, or
Streptomyces. Under optimum conditions (ie, prolonged
occlusion, hyperhidrosis, increased skin surface pH), these bacteria
grow and produce proteinases that destroy the stratum corneum, creating
pits. D congolensis liberates keratinases in appropriate
substrate. K sedentarius has been found to produce 2
keratin-degrading enzymes. They are protease P1 (30 kd) and P2 (50 kd). The foot odor associated with Foot odor is
conume to be the production of sulfur-compound by-products, such as thiols,
sulfides, and thioesters.
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